U.S.-led airstrikes killed three civilians and wounded several more east of Shaddadi town in northeastern Hasaka province, residents said Tuesday.
The attack was in retaliation to a deadly four ISIS suicide bombing on Rajm al-Salibi, the location of a checkpoint and refugee camp near the border with Iraq, led to fierce clashes, injuring dozens, the Syrian Observatory for Human Rights said.
Rajm al-Salibi is held by the U.S.-backed Syrian Democratic Forces (SDF) in northeast Syria killed at least 38 people, including 23 civilians.
The SDF battled Islamic State since dawn in nearby areas of Hasaka province, which Kurdish forces largely control, it said.
An adviser to the SDF, Nasser Haj Mansour, confirmed to Reuter that several civilians died, including people escaping Islamic State in Syria's Deir al-Zor and in Iraq.
The International Rescue Committee said the wounded were taken to hospital inside Hasaka and several children were killed. Thousands of people have fled Iraq for the Rajm al-Salibi border crossing and another camp further north in recent months, the global aid agency said