Syrian pro-government forces now hold more than a fifth of the country's strategic desert, the army said Saturday, after reaching the eastern border with Iraq for the first time since 2015.
The desert, known as the "Badiya", extends over some 90,000 square kilometers (35,000 square miles) from central Syria to the borders with Iraq and Jordan to the east and southeast.
Since 2015, much of the Badiya has been held by ISIS, but Syria's army has been chipping away at it for months.
On Friday, they reached the country's eastern frontier with Iraq for the first time in two years.
"In cooperation with our allies, our units have captured a large number of locations and strategic positions in the Badiya, amounting to an area of 20,000 square kilometers," the general command of the army said on Saturday.
"This important achievement represents a strategic shift in the fight against terrorism and a launching pad to broaden military operations in the Badiya and along the borders with Iraq," said the statement, distributed on state media.
State news agency SANA had reported on Friday that army units set up positions northeast of the At-Tanaf garrison, currently used by the U.S.-led coalition bombing ISIS to train Syrian rebels to fight the militants.
The coalition has established a "de-confliction" zone extending 55 kilometers (34 miles) from the garrison, in which pro-regime and allied Russian forces are not supposed to operate.
The U.S.-led alliance has in recent weeks conducted three strikes against pro-regime forces it deemed to be threatening At-Tanaf.
Syria's army on Saturday accused the coalition of carrying out the bombing raids in an attempt to slow the regime's fight against ISIS.
"We once again warn of the dangers of repeated attacks by the so-called international coalition and its attempts to obstruct the advances of the Syrian army and its allies," the command said.
Syria's conflict erupted in March 2011 with protests against the rule of President Bashar Assad.
It has since evolved into a complex, multi-front war that has drawn in international powers and left more than 320,000 people dead.